How common is exercise-induced anaphylaxis?
Exercise-induced anaphylaxis (EIA) is a rare disorder in which individuals develop immunoglobulin E (IgE)–mediated hypersensitivity in conjunction with exercise, causing anaphylaxis. The lifetime prevalence of EIA is about 0.05%.
Is exercise-induced anaphylaxis life-threatening?
Summary Exercise-induced anaphylaxis (EIAn) is a rare and potentially fatal syndrome associated with exercise. It is the most serious and potentially life-threatening hypersensitivity phenomenon for athletes of all sports.
How is exercise-induced anaphylaxis diagnosed?
The diagnosis of EIAn and FDEIAn is achieved by means of a challenge, with physical exercise alone for EIAn, and with the assumption of the suspected food followed by physical exercise for FDEIAn; in cases of doubtful results, a double-blind placebo-controlled combined food–exercise challenge should be performed.