What causes exercise induced collapse in dogs?
EIC is caused by a mutation in dynamin 1 gene (DNM1 c. 767G>T). It is inherited as an autosomal recessive disorder, which means that both males and females are affected equally, and that two copies of the mutation are needed to cause the disease.
At what age does exercise induced collapse in dogs?
Signs first become apparent in young dogs — usually between five months and three years of age (average 14 months). Affected dogs exhibiting symptoms of collapse are usually described as extremely fit, muscular, prime athletic specimens with an excitable temperament and lots of drive.
Is EIC in dogs fatal?
Although most dogs recover quickly, within 30 minutes, severe episodes of EIC can be fatal. Dogs affected by the condition often experience numerous recurrences, although their gait and behavior return to normal between episodes.